Supertrends in Anti–Aging discusses the possibilities of extending the human lifespan and healthspan, a long-time dream of humanity that could never quite be realized – until now. Anti-aging technology is on the verge of significant breakthroughs. No matter whether you are an investor, working in biotechnology or simply want to understand how this supertrend will impact businesses, this report is the place to go for understanding the science, the benefits, and the challenges behind the fast-developing research field of anti-aging.
The history of anti-aging technology and a timeline of major breakthroughs
A description of the mechanisms of aging at the cellular level
An overview of the technological advances and challenges within each of the nine hallmarks of aging
Insights on market demographics and major players
An analysis on consumer demographics and impact on society
Insights into the active players in the field, their technological background, challenges and road to success
In the preface, our founder Lars Tvede explains why anti-aging technology is a Supertrend. He discusses the growing interest in the concept of delaying the onset of aging and the cultural importance of longevity throughout history, from the quest for a Fountain of Youth to scientific breakthroughs and finally the likely impact that anti aging interventions will have on technology, finance, and the future of humanity.
The introduction offers a brief summary of the historical interest in aging and the science behind it. From prehistory and Ancient Greece to the Industrial Revolution, the process of aging has been of interest to all generations; but until recently, the biological causes of aging on a cellular level were a mystery. We will outline causes and mechanisms of aging to set a foundation for the prevalence of the nine hallmarks of aging that are covered later in the report. The first scientific insights into the subject of aging were only gained as recently as 1908 when Elie Metchnikoff coined the term “gerontology” for the study of old age, although aging has been a concern to humanity as far back in time as Ancient Greece. In the timeline of this chapter you will find the contemporary breakthroughs in the field of anti-aging research as well as the key players in determining the hallmarks of aging presented in subsequent chapters. Finally, we will present the modern notion of aging as a disease as we dissect the possible cures to this omnipresent ailment.
Scientific knowledge on the subject of aging was acquired as recently as 1908, although aging was a concern since the ancient Greeks. In this timeline you will find the contemporary breakthroughs in the field of Anti Aging research as well as the key players in determining the hallmarks of aging presented in subsequent chapters.
This dynamic report is structured along the nine Hallmarks of Aging identified by López-Otín et al. in their eponymous paper published in 2013. Each section describes one of the cellular and genetic causes of aging and offers an explanation of how their effects to the human body, the benefits that addressing them brings to the organism, and the consequences and current challenges of such treatments. Finally, each hallmark is complemented by a list of companies currently working on addressing aging through that particular focus, although some entities are applying a wider scope on anti-aging by working on more than one hallmark.
Preventing the loss of key DNA sections.
Using senolytic drugs to kill and remove “zombie cells”.
Generating multi-purpose “rejuvenation cells”.
DNA altering through methylation as a metric for biological age.
Helping mitochondria consume nutrients and oxygen to increase health and lifespan.
Ensuring cells can repair themselves and each other.
Maintaining a fully functional immune system.
Reducing errors in DNA replication.
After the comprehensive overview of the Hallmarks of Aging, the dynamic report provides a conclusion that summarizes all the aforementioned content. It includes an outline of the main demographics that stand to benefit from successful results of harnessing and artificially controlling the hallmarks of aging. Finally, we will provide an assessment of the current challenges and obstacles faced by companies and research facilities that are working on “curing” aging. This conclusion will also receive an update with each iteration of this dynamic report as the technological development behind the hallmarks of aging is ongoing and there are breakthroughs every day, which will be reflected in this product.
To wrap up our report, Lars Tvede provides some food for thought on the effects of the innovations that Anti-Aging technology will bring to modern society. Lars also forecasts what the consequences of having a fountain of youth will currently be, and how we stand to benefit (or suffer) from an extended lifespan as components of a workforce, providers of goods and services, and members of a constantly changing society with prominent extremes and an uncertain financial landscape.
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